Generally speaking, a clinician’s understanding of genetic data is limited when compared to oncologists, genetic counselors, molecular pathologists and researchers who are the most knowledgeable about this specialty. Community physicians and other specialists are just beginning their learning in this complex field.
Genetic results that contain clinically actionable variants need to be filtered from variants of unknown significance and discretely interfaced into the electronic medical record.
The data needs to be stored chronologically and linked to other genetic test results in order to be most effective. This proposed requirement is especially important for somatic test results that shift over time as cancer tumors develop drug resistance and continue to mutate. Germ line test results are much more constant over a patient’s lifetime but the relation of tumor specific markers to inherited markers is becoming more important in drug selection and targeted therapies.
To achieve reliable EMR integration, genetic testing labs must accept inbound electronic orders from providers’ EHRs and return not only rich textual summaries that contain annotations, metadata and literature references but also discrete genetic variant specific measurements and attributes.
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